Benzyloxy carbonyl-PEG3-t-butyl ester

Names

[ CAS No. ]:
1835759-86-8

[ Name ]:
Benzyloxy carbonyl-PEG3-t-butyl ester

[Synonym ]:
MFCD29042340

Biological Activity

[Description]:

Benzyloxy carbonyl-PEG3-C2-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> PROTAC >> PROTAC Linker

[Target]

Alkyl/ether

[In Vitro]

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[References]

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₁H₃₂O₇

[ Molecular Weight ]:
396.47

Related Compounds

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