METHYL 8-CHLORO-6-(TRIFLUOROMETHYL)IMIDAZO[1,2-A]PYRIDINE-7-CARBOXYLATE

Names

[ Name ]:
METHYL 8-CHLORO-6-(TRIFLUOROMETHYL)IMIDAZO[1,2-A]PYRIDINE-7-CARBOXYLATE

[Synonym ]:
(R)-Stericol(R)
(R)-Greene's alcohol
(R)-(+)-STERICOL
Methyl 8-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridine-7-carboxylate
1-(2,4,6-triisopropylphenyl)ethanol
(R)-1-(2,4,6-triisopropylphenyl)ethanol

Chemical & Physical Properties

[ Melting Point ]:
86-90ºC

[ Molecular Formula ]:
C₁₀H₆ClF₃N₂O₂

[ Molecular Weight ]:
278.61500

[ Exact Mass ]:
278.00700

[ PSA ]:
43.60000

[ LogP ]:
2.79310

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

New asymmetric approach to natural pyrrolizidines: synthesis of (+)-amphorogynine A, (+)-amphorogynine D, and (+)-retronecine.

J. Org. Chem. 70 , 8352-8363, (2005)

Three natural pyrrolizidines, (+)-amphorogynines A and D and (+)-retronecine, have been prepared from a common lactam intermediate. This central compound, in turn, was synthesized in diastereomericall...

A New Asymmetric Carbon-Carbon Bond Forming Reaction: Four-Component Stereoselective Synthesis of (Z)-4,6-Dihydroxy-3-methylalk-2-enyl Methyl Sulfones This work was supported by the Swiss National Science Foundation.

Angew. Chem. Int. Ed. Engl. 39 , 1806, (2000)

Hamel, M., et al.

Tetrahedron Asymmetry 16 , 3406-3415, (2005)