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P62-mediated mitophagy inducer

Names

[ CAS No. ]:
1809031-84-2

[ Name ]:
P62-mediated mitophagy inducer

[Synonym ]:
MFCD31620757

Biological Activity

[Description]:

P62-mediated mitophagy inducer is a mitophagy regulator which activates mitophagy without recruiting Parkin or collapsing ΔΨm and retains activity in cells devoid of a fully functional PINK1/Parkin pathway[1].

[Related Catalog]:

Signaling Pathways >> Autophagy >> Mitophagy
Research Areas >> Neurological Disease

[Target]

mitophagy[1]


[References]

[1]. East DA, et al. PMI: a ΔΨm independent pharmacological regulator of mitophagy. Chem Biol. 2014 Nov 20;21(11):1585-96.

Chemical & Physical Properties

[ Molecular Formula ]:
C14H9IN4O2

[ Molecular Weight ]:
392.15

Safety Information

[ Hazard Codes ]:
Xn


Related Compounds

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