EBI-1051

Names

[ CAS No. ]:
1801896-05-8

[ Name ]:
EBI-1051

Biological Activity

[Description]:

EBI-1051 is a highly potent and orally efficacious MEK inhibitor with an IC50 of 3.9 nM.

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> MAPK/ERK Pathway >> MEK

[Target]

IC50: 3.9 nM (MEK)[1]

[References]

[1]. Lu B, et al. Discovery of EBI-1051: A novel and orally efficacious MEK inhibitor with benzofuran scaffold. Bioorg Med Chem. 2018 Feb 1;26(3):581-589.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₈H₁₅F₂IN₂O₅

[ Molecular Weight ]:
504.22

Related Compounds

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