Alcaftadine-D3

Names

[ CAS No. ]:
1794775-80-6

[ Name ]:
Alcaftadine-D3

[Synonym ]:
5H-Imidazo[2,1-b][3]benzazepine-3-carboxaldehyde, 6,11-dihydro-11-[1-(methyl-d3)-4-piperidinylidene]-
11-[1-(2H3)Methyl-4-piperidinylidene]-6,11-dihydro-5H-imidazo[2,1-b][3]benzazepine-3-carbaldehyde

Biological Activity

[Description]:

Alcaftadine-D3 (R89674-D3) is a deuterium labeled Alcaftadine. Alcaftadine (HY-17039) is a H1 histamine receptor antagonist[1].

[Related Catalog]:

Signaling Pathways >> Immunology/Inflammation >> Histamine Receptor
Research Areas >> Endocrinology
Research Areas >> Inflammation/Immunology
Signaling Pathways >> GPCR/G Protein >> Histamine Receptor

[References]

[1]. Namdar, R. and C. Valdez, Alcaftadine: a topical antihistamine for use in allergic conjunctivitis. Drugs Today (Barc), 2011. 47(12): p. 883-90.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
556.2±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C19H18D3N3O

[ Molecular Weight ]:
310.408

[ Flash Point ]:
290.2±32.9 °C

[ Exact Mass ]:
310.187286

[ LogP ]:
3.20

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.663

[ Storage condition ]:
2-8°C

Related Compounds