Myelin Basic Protein (83-99) (bovine) trifluoroacetate salt

Names

[ Name ]:
Myelin Basic Protein (83-99) (bovine) trifluoroacetate salt

[Synonym ]:
L-α-Glutamyl-L-asparaginyl-L-prolyl-L-valyl-L-valyl-L-histidyl-L-phenylalanyl-L-phenylalanyl-L-lysyl-L-asparaginyl-L-isoleucyl-L-valyl-L-threonyl-L-prolyl-L-arginyl-L-threonyl-L-proline
L-Proline, L-α-glutamyl-L-asparaginyl-L-prolyl-L-valyl-L-valyl-L-histidyl-L-phenylalanyl-L-phenylalanyl-L-lysyl-L-asparaginyl-L-isoleucyl-L-valyl-L-threonyl-L-prolyl-L-arginyl-L-threonyl-

Biological Activity

[Description]:

MBP (83-99) is a MBP-specific T cell lines recognizing the immunodominant epitope. MBP (83-99) induces proliferation and IFN-γ secreting of T cells[1][2].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

[In Vitro]

MBP (83-99) is the immunodominant region of MBP restricted by HLA-DR2[1]. MBP (83-99) induces proliferation of a human T cell line[2].

[In Vivo]

MBP(83-99) (50 µg; subcutaneous injection; once) generates weak IFN-γ secreting T cells in immunize SJL/J mice[2].

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Molecular Formula ]:
C₉₃H₁₄₃N₂₅O₂₄

[ Molecular Weight ]:
1995.284

[ Exact Mass ]:
1994.073730

[ LogP ]:
0.93

[ Index of Refraction ]:
1.667

Related Compounds

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