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27-Methyl withaferin A

Names

[ CAS No. ]:
1777780-93-4

[ Name ]:
27-Methyl withaferin A

Biological Activity

[Description]:

27-Methyl withaferin A (comppund 26) is an apoptosis inducer with anticancer effects. 27-Methyl withaferin A shows antiproliferative effects against HeLa, A-549 and MCF-7 human tumor cell lines with IC50 values of 3.2 μM, 4.2 μM and 1.4 μM, respectively[1].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis
Research Areas >> Cancer

[References]

[1]. Gabriel G Llanos, et al. Structure-based design, synthesis, and biological evaluation of withaferin A-analogues as potent apoptotic inducers. Eur J Med Chem. 2017 Nov 10;140:52-64.

Chemical & Physical Properties

[ Molecular Formula ]:
C29H40O6

[ Molecular Weight ]:
484.62

Related Compounds