Cytidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-5-methyl-

Names

[ Name ]:
Cytidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-5-methyl-

[Synonym ]:
5'-O-Dimethoxytrityl-2'-deoxy-5-methylcytidine
5'-O-dimethoxytrityl-5-methyl-2'-deoxycytidine

Biological Activity

[Description]:

2'-Deoxy-5'-O-DMT-5-methylcytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Gowher H, et al. Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy. Cancer Biol Ther. 2004 Nov;3(11):1062-8.

Chemical & Physical Properties

[ Density]:
1.28±0.1 g/cm3(Predicted)

[ Boiling Point ]:
720.3±70.0 °C(Predicted)

[ Melting Point ]:
215-217 °C

[ Molecular Formula ]:
C₃₁H₃₃N₃O₆

[ Molecular Weight ]:
543.61

[ Exact Mass ]:
543.23700

[ PSA ]:
119.05000

[ LogP ]:
4.15060

Cytidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-5-methyl-

Names

Biological Activity

Chemical & Physical Properties

Synthetic Route

Click to get detail synthetic route