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Anisodamine

Names

[ CAS No. ]:
17659-49-3

[ Name ]:
Anisodamine

[Synonym ]:
(1S)-6-Hydroxy-8-methyl-8-azabicyclo[3.2.1]oct-3-yl tropate
6-Hydroxy-8-methyl-8-azabicyclo[3.2.1]oct-3-yl tropate
benzeneacetic acid, α-(hydroxymethyl)-, (1R)-6-hydroxy-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester
Benzeneacetic acid, α-(hydroxymethyl)-, 6-hydroxy-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester
3-Hydroxy-2-phenyl-propionic acid 6-hydroxy-8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester
α-(hydroxymethyl)benzeneacetic acid 6-hydroxy-8-methyl-8-azabicyclo(3.2.1)oct-3-yl ester
6-hydroxyhyoscyamine
Anisodamine

Biological Activity

[Description]:

Racanisodamine is one of the racemic isomers of anisodamine, resembles anisodamine in pharmacological effect. Racanisodamine is a non-selective muscarinic antagonist, used as a component of eye drops for myopic control[1].

[Related Catalog]:

Signaling Pathways >> Neuronal Signaling >> mAChR
Signaling Pathways >> GPCR/G Protein >> mAChR
Research Areas >> Neurological Disease

[References]

[1]. Chen Z, et al. Effects of 0.05% racanisodamine on pupil size and accommodation. Optom Vis Sci. 2010 Dec;87(12):966-70.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
474.6±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C17H23NO4

[ Molecular Weight ]:
305.369

[ Flash Point ]:
240.8±28.7 °C

[ Exact Mass ]:
305.162720

[ PSA ]:
70.00000

[ LogP ]:
0.25

[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C

[ Index of Refraction ]:
1.600

Safety Information

[ Hazard Codes ]:
Xi

Synthetic Route

Click to get detail synthetic route

Related Compounds