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REVERSIN 205

Names

[ CAS No. ]:
174630-05-8

[ Name ]:
REVERSIN 205

[Synonym ]:
[Boc-Glu(Obzl)]2-Lys-Ome
Reversin 205

Biological Activity

[Description]:

Reversin 205 ([Boc-Glu(Obzl)]2-Lys-Ome) is a P-glycoprotein (ABCB1) inhibitor. Reversin 205 is a peptide chemosensitizer[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Membrane Transporter/Ion Channel >> P-glycoprotein

[References]

[1]. Navarro A, et al. Abcb and Abcc transporter homologs are expressed and active in larvae and adults of zebra mussel and induced by chemical stress. Aquat Toxicol. 2012 Oct 15;122-123:144-52.  

Chemical & Physical Properties

[ Molecular Formula ]:
C41H58N4O12

[ Molecular Weight ]:
798.91900

[ Exact Mass ]:
798.40500

[ PSA ]:
227.72000

[ LogP ]:
6.85390

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Related Compounds