4'-C-azido-2'-deoxy-2'-fluoro-beta-D-arabinouridine

Names

[ Name ]:
4'-C-azido-2'-deoxy-2'-fluoro-beta-D-arabinouridine

[Synonym ]:
1-[(2R,3S,4R,5R)-5-Azido-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydro-2-furanyl]-2,4(1H,3H)-pyrimidinedione

Biological Activity

[Description]:

4’-Azido-2’-deoxy-2’-fluoro-beta-D-arabinouridine is a uridine analogue. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

Research Areas >> Others

[References]

[1]. Connolly GP, et al. Uridine and its nucleotides: biological actions, therapeutic potentials. Trends Pharmacol Sci. 1999 May;20(5):218-25.

Chemical & Physical Properties

[ Molecular Formula ]:
C₉H₁₀FN₅O₅

[ Molecular Weight ]:
287.20

[ Exact Mass ]:
287.066589

[ PSA ]:
154.30000

[ LogP ]:
-0.27

Related Compounds

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