5,5'-Dinitro BAPTA AM

Names

[ CAS No. ]:
172646-47-8

[ Name ]:
5,5'-Dinitro BAPTA AM

Biological Activity

[Description]:

5,5'-Dinitro BAPTA AM is a membrane-permeant, high-affinity calcium chelator, it can be used for investigation of the role of cytosolic Ca2+. 5,5'-Dinitro BAPTA AM can be loaded by incubation into live cells, and is cleaved by cytosolic esterases to liberate the active tetra-carboxylate ligand[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[In Vitro]

5,5'-Dinitro BAPTA AM (50 μM; 20 min) attenuates evoked field excitatory postsynaptic potentials[1].

[References]

[1]. Ouanounou A, et al. Accumulation and extrusion of permeant Ca2+ chelators in attenuation of synaptic transmission at hippocampal CA1 neurons. Neuroscience. 1996 Nov;75(1):99-109.

Chemical & Physical Properties

No Any Chemical & Physical Properties

Related Compounds