IR820

Names

[ Name ]:
IR820

[Synonym ]:
IR-820,2-[2-[2-Chloro-3-[[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benzo[e]indol-2-ylidene]-ethylidene]-1-cyclohexen-1-yl]-ethenyl]-1,1-dimethyl-3-(4-sulfobutyl)-1H-benzo[e]indolium hydroxide inne
2-(2-(2-Chloro-3-((1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benzo[e]indol-2-ylidene)ethylidene)-1-cyclohexen-1-yl]
New indocyanine Green
IR-820
2-[2-[2-Chloro-3-[[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benzo[e]indol-2-ylidene]-ethylidene]-1-cyclohexen-1-yl]-ethenyl]-1,1-dimethyl-3-(4-sulfobutyl)-1H-benzo(e)indolium hydroxide,inner salt
2-[2-[2-chloro-3-[[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2h-benzo[e]indol-2-ylidene]-ethylidene]-1-cyclohexen-1-yl]-ethenyl]-1,1-dimethyl-3-(4-sulfobutyl)-1h-benzo[e]indolium hydroxide inner salt,sodium salt
MFCD04038859
IR820

Biological Activity

[Description]:

IR-820 (New Indocyanine Green) is an infrared blood pool contrast agent. IR-820 also is normally used as a laser and near-infrared dye to detect and quantify diseased tissue in live animals[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[In Vitro]

Guidelines (Following is our recommended protocol. This protocol only provides a guideline, and should be modified according to your specific needs). 体内[1]： 1. 将粉末状的 IR-820 与磷酸盐缓冲液 (PBS) 新鲜混合至终浓度为 0.2 mM，取 100 μL 此溶液注射到实验动物中。 2.使用 2 组四只无毛 SKHi/sKHl 小鼠。第一组通过静脉尾静脉注射 IR-820，而第二组通过腹膜内注射。 3. IR-820 的最大激发和发射波长分别为 710 nm 和 820 nm。两组连续成像 8 天。

[References]

[1]. Suresh I Prajapati, et al. Near-infrared imaging of injured tissue in living subjects using IR-820. Mol Imaging. 2009 Jan-Feb;8(1):45-54.

Chemical & Physical Properties

[ Melting Point ]:
>300ºC

[ Molecular Formula ]:
C₄₆H₅₀ClN₂NaO₆S₂

[ Molecular Weight ]:
849.47200

[ Exact Mass ]:
848.27000

[ PSA ]:
137.41000

[ LogP ]:
12.04650

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ RIDADR ]:
NONH for all modes of transport