3,4-Dibenzyloxyphenethylamine hydrochloride

Names

[ Name ]:
3,4-Dibenzyloxyphenethylamine hydrochloride

[Synonym ]:
2-(3,4-bisbenzyloxyphenyl)ethylamine hydrochloride
EINECS 216-924-4
MFCD00012629
H2N-dopamine-Bn2*HCl
3,4-bis(benzyloxy)-phenethylamine hydrochloride
3,4-(DIBENZYLOXY)PHENETHYLAMINE HYDROCHLORIDE
2-(3,4-dibenzyloxyphenyl)ethylamine hydrochloride
2-(3,4-bis (phenylmethoxy)phenyl)ethylamine hydrochloride

Chemical & Physical Properties

[ Density]:
1.128g/cm3

[ Boiling Point ]:
493.4ºC at 760 mmHg

[ Melting Point ]:
131-133ºC(lit.)

[ Molecular Formula ]:
C₂₂H₂₄ClNO₂

[ Molecular Weight ]:
369.88400

[ Flash Point ]:
279.8ºC

[ Exact Mass ]:
369.15000

[ PSA ]:
44.48000

[ LogP ]:
5.84810

[ Vapour Pressure ]:
7.05E-10mmHg at 25°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS05, GHS07, GHS09

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H315-H318-H335-H410

[ Precautionary Statements ]:
P261-P273-P280-P305 + P351 + P338-P501

[ Hazard Codes ]:
Xn,N

[ Risk Phrases ]:
22-37/38-41-50/53

[ Safety Phrases ]:
24/25

[ RIDADR ]:
UN 3077 9 / PGIII

[ WGK Germany ]:
3

[ HS Code ]:
2922199090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2922199090

[ Summary ]:
2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Design, synthesis and brain uptake of LAT1-targeted amino acid prodrugs of dopamine.

Pharm. Res. 30(10) , 2523-37, (2013)

Drug delivery to the brain is impeded by the blood-brain barrier (BBB). Here, we attempted to enhance the brain uptake of cationic dopamine by utilizing the large amino acid transporter 1 (LAT1) at th...

Tetrahydroisoquinoline derivatives containing a benzenesulfonamide moiety as potent, selective human beta3 adrenergic receptor agonists.

Bioorg. Med. Chem. Lett. 10(20) , 2283-6, (2000)

Tetrahydroisoquinoline derivatives containing a 4-(hexylureido)benzenesulfonamide were examined as human beta3 adrenergic receptor (AR) agonists. Notably, 4,4-biphenyl derivative 9 was a 6 nM full ago...