BMS-242
Names
[ CAS No. ]:
1675204-51-9
[ Name ]:
BMS-242
Biological Activity
[Description]:
A potent PD-1/PD-L1 interaction inhibitor with IC50 of 6-100 nM in a homogenous time-resolved fluorescence binding assay.
[References]
References 1. Guzik K, et al. J Med Chem. 2017 Jul 13;60(13):5857-5867. 2. Zak KM, et al. Oncotarget. 2016 May 24;7(21):30323-35. 3. Chupak, L.S., and Zheng, X. Compounds useful as immunomodulators. PCT/US2014/053695, (2015). View Related Products by Target PD-1/PD-L1
Chemical & Physical Properties
[ Molecular Formula ]:
C28H35NO4
[ Molecular Weight ]:
449.591
Related Compounds
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