bisphenol A diglycidyl ether
Names
[ CAS No. ]:
1675-54-3
[ Name ]:
bisphenol A diglycidyl ether
[Synonym ]:
2,2'-[(1-methylethylidene)bis(4,1-phenyleneoxymethylene)]bisoxirane
Diglycidyl bisphenol A ether
Diglycidyl ether of bisphenol A
EINECS 216-823-5
2,2'-[Propane-2,2-diylbis(4,1-phenyleneoxymethylene)]dioxirane
Diglycidyl bisphenol A
DGEBPA
2,2-Bis(4-hydroxyphenyl)propane Diglycidyl Ether
2,2-Bis[4-(glycidyloxy)phenyl]propane
2,2-Bis[4-(2,3-epoxypropoxy)phenyl]propane
2,2-Bis(4'-glycidyloxyphenyl)propane
Oxirane, 2,2'-[(1-methylethylidene)bis(4,1-phenyleneoxymethylene)]bis-
Diglycidyl ether of 2,2-bis(p-hydroxyphenyl)propane
2,2'-[propane-2,2-diylbis(benzene-4,1-diyloxymethanediyl)]dioxirane
MFCD03792911
2,2'-[2,2-Propanediylbis(4,1-phenyleneoxymethylene)]dioxirane
Bisphenol A diglycidyl ether
2,2-Bis(4-glycidyloxyphenyl)propane
4,4′-Isopropylidenediphenol diglycidyl ether
Propane, 2,2-bis[p-(2,3-epoxypropoxy)phenyl]-
D.E.R.™ 332
Propane, 2,2-bis[(p-2,3-epoxypropoxy)phenyl]-
2-[[4-[2-[4-(oxiran-2-ylmethoxy)phenyl]propan-2-yl]phenoxy]methyl]oxirane
4,4'-Isopropylidenediphenol diglycidyl ether
Diglycidyl ether of 2,2-bis(4-hydroxyphenyl)propane
dgeba
Diglycidyl ether of 4,4'-isopropylidenediphenol
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
487.0±35.0 °C at 760 mmHg
[ Melting Point ]:
40-44ºC
[ Molecular Formula ]:
C21H24O4
[ Molecular Weight ]:
340.413
[ Flash Point ]:
148.5±32.8 °C
[ Exact Mass ]:
340.167450
[ PSA ]:
43.52000
[ LogP ]:
3.95
[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C
[ Index of Refraction ]:
1.569
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TX3800000
- CHEMICAL NAME :
- Propane, 2,2-bis(p-(2,3-epoxypropoxy)phenyl)-
- CAS REGISTRY NUMBER :
- 1675-54-3
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 22
- MOLECULAR FORMULA :
- C21-H24-O4
- MOLECULAR WEIGHT :
- 340.45
- WISWESSER LINE NOTATION :
- T3OTJ B1OR D- 2X
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Open irritation test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 11300 uL/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2200 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Gastrointestinal - hypermotility, diarrhea Nutritional and Gross Metabolic - weight loss or decreased weight gain
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 15600 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Gastrointestinal - hypermotility, diarrhea Nutritional and Gross Metabolic - weight loss or decreased weight gain
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 4 gm/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Gastrointestinal - hypermotility, diarrhea Nutritional and Gross Metabolic - weight loss or decreased weight gain
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 1980 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Gastrointestinal - hypermotility, diarrhea Nutritional and Gross Metabolic - weight loss or decreased weight gain
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 20 gm/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Gastrointestinal - hypermotility, diarrhea Nutritional and Gross Metabolic - weight loss or decreased weight gain
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 166 gm/kg/2Y-I
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Endocrine - thyroid tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 312 gm/kg/2Y-I
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors Reproductive - Tumorigenic effects - ovarian tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 312 gm/kg/2Y-I
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Skin and Appendages - tumors
MUTATION DATA
- TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Bacteria - Salmonella typhimurium
- DOSE/DURATION :
- 33 ug/plate
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 172,105,1986 *** REVIEWS *** IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 47,237,1989 IARC Cancer Review:Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 47,237,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - T0018 No. of Facilities: 163 (estimated) No. of Industries: 8 No. of Occupations: 10 No. of Employees: 1413 (estimated) NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83440 No. of Facilities: 2505 (estimated) No. of Industries: 54 No. of Occupations: 54 No. of Employees: 32393 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83440 No. of Facilities: 1109 (estimated) No. of Industries: 28 No. of Occupations: 38 No. of Employees: 25257 (estimated) No. of Female Employees: 4341 (estimated)
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H317-H319
[ Precautionary Statements ]:
P280-P305 + P351 + P338
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
Xi: Irritant;
[ Risk Phrases ]:
R36/38
[ Safety Phrases ]:
28-37/39
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
1
[ RTECS ]:
TX3800000
[ HS Code ]:
2910900090
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2910900090
[ Summary ]:
2910900090. epoxides, epoxyalcohols, epoxyphenols and epoxyethers, with a three-membered ring, and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%
Articles
Autophagy 11(1) , 100-12, (2015)
Autophagy is one of the main mechanisms in the pathophysiology of neurodegenerative disease. The accumulation of autophagic vacuoles (AVs) in affected neurons is responsible for amyloid-β (Aβ) product...
Phenotypic characterization of a novel double knockout PknI/DacB2 from Mycobacterium tuberculosis.Microbiol. Res. 170 , 255-62, (2014)
Serine/threonine protein kinases play a major role in peptidoglycan biosynthesis in Mycobacterium tuberculosis. To explore the mechanism in detail, in the present study, we have constructed a double k...
Ocular surface reconstruction with a tissue-engineered nasal mucosal epithelial cell sheet for the treatment of severe ocular surface diseases.Stem Cells Transl. Med. 4(1) , 99-109, (2014)
Severe ocular surface diseases (OSDs) with severe dry eye can be devastating and are currently some of the most challenging eye disorders to treat. To investigate the feasibility of using an autologou...