N-Boc-dolaproine-methyl

Names

[ Name ]:
N-Boc-dolaproine-methyl

Biological Activity

[Description]:

N-Boc-dolaproine-methyl is the amino acid residue of the pentapeptide Dolastatin 10 (HY-15580). Dolastatin 10 inhibits tubulin polymerization and mitosis and has anticancer activity[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[References]

[1]. Almeida W P, et al. An easy and stereoselective synthesis of N-Boc-dolaproine via the Baylis–Hillman reaction[J]. Tetrahedron letters, 2003, 44(5): 937-940.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₄H₂₅NO₅

[ Molecular Weight ]:
287.35200

[ Exact Mass ]:
287.17300

[ PSA ]:
76.07000

[ LogP ]:
1.49380

Related Compounds

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