PSB CB5

Names

[ Name ]:
PSB CB5

[Synonym ]:
(2Z)-2-{3-[(4-Chlorobenzyl)oxy]benzylidene}-6,7-dihydro-5H-imidazo[2,1-b][1,3]thiazin-3(2H)-one
5H-Imidazo[2,1-b][1,3]thiazin-3(2H)-one, 2-[[3-[(4-chlorophenyl)methoxy]phenyl]methylene]-6,7-dihydro-, (2Z)-
CID-85469571

Biological Activity

[Description]:

PSB-CB5 is a potent and selective antagonist of GRP18. PSB-CB5 has the potential for the research of metabolic disease and obesity[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

[References]

[1]. Kotańska M, et al. Effects of GPR18 Ligands on Body Weight and Metabolic Parameters in a Female Rat Model of Excessive Eating. Pharmaceuticals (Basel). 2021;14(3):270.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
549.9±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₀H₁₇ClN₂O₂S

[ Molecular Weight ]:
384.879

[ Flash Point ]:
286.4±32.9 °C

[ Exact Mass ]:
384.069916

[ LogP ]:
4.43

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.672

Related Compounds

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