GNE-8505

Names

[ CAS No. ]:
1620573-48-9

[ Name ]:
GNE-8505

Biological Activity

[Description]:

GNE-8505 is an orally available inhibitor of Dual leucine zipper kinase (DLK)[1].

[Related Catalog]:

Research Areas >> Neurological Disease
Signaling Pathways >> MAPK/ERK Pathway >> MAP3K

[Target]

DLK[1]


[References]

[1]. Le Pichon CE, et al. Loss of dual leucine zipper kinase signaling is protective in animal models of neurodegenerative disease. Sci Transl Med. 2017 Aug 16;9(403). pii: eaag0394.

Chemical & Physical Properties

[ Molecular Formula ]:
C21H24F3N5O

[ Molecular Weight ]:
419.44

Related Compounds