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Lupeol acetate

Names

[ CAS No. ]:
1617-68-1

[ Name ]:
Lupeol acetate

[Synonym ]:
3-O-acetyl-lupeol
lup-20(29)-en-3-yl acetate
(3beta)-lup-20(29)-en-3-yl acetate
lupeol acetate
3-acetoxy-28-deoxobetulin
3-Acetyllupeol
Lupeyl acetate
LUPENYL ACETATE

Biological Activity

[Description]:

Lupeol acetate, a derivative of Lupeol, suppresses the progression of rheumatoid arthritis (RA) by inhibiting the activation of macrophages and osteoclastogenesis through downregulations of TNF-α, IL-1β, MCP-1, COX-2, VEGF and granzyme B[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Inflammation/Immunology

[References]

[1]. Wang WH, et al. Lupeol acetate ameliorates collagen-induced arthritis and osteoclastogenesis of mice through improvement of microenvironment. Biomed Pharmacother. 2016;79:231-240.

Chemical & Physical Properties

[ Density]:
1.01g/cm3

[ Boiling Point ]:
502.7ºC at 760mmHg

[ Melting Point ]:
218ºC

[ Molecular Formula ]:
C32H52O2

[ Molecular Weight ]:
468.75400

[ Flash Point ]:
254.7ºC

[ Exact Mass ]:
468.39700

[ PSA ]:
26.30000

[ LogP ]:
8.59560

[ Vapour Pressure ]:
3.1E-10mmHg at 25°C

[ Index of Refraction ]:
1.524

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds