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PHT-7.3

Names

[ CAS No. ]:
1614225-93-2

[ Name ]:
PHT-7.3

Biological Activity

[Description]:

PHT-7.3 is a selective inhibitor of connector enhancer of kinase suppressor of Ras 1 (Cnk1) pleckstrin homology (PH) domain, blocks the growth of mutant KRAS cells and tumors[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[Target]

Cnk1 PH-domain[1]


[References]

[1]. Indarte M ，et al. An Inhibitor of the Pleckstrin Homology Domain of CNK1 Selectively Blocks the Growth of Mutant KRAS Cells and Tumors. Cancer Res. 2019 Jun 15;79(12):3100-3111.

Chemical & Physical Properties

[ Molecular Formula ]:
C24H23N3O3S

[ Molecular Weight ]:
433.52

Related Compounds