Autotaxin-IN-13

Names

[ Name ]:
Autotaxin-IN-13

Biological Activity

[Description]:

Autotaxin-IN-13 ( ATX-i) is a highly potent, selective Autotaxin inhibitor with IC50 of 6 nM.Autotaxin showed sufficient oral bioavailability and low plasma clearance in vivo as well as a suitable half-life to allow for bid or food admix dosing.

[References]

1. Daniel Hunziker, et al. Front Pharmacol. 2022 Jan 18;12:699535.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₂H₂₀F₃N₅O₄

[ Molecular Weight ]:
475.428

Related Compounds

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