H-Cys-Val-2-Nal-Met-OH

Names

[ Name ]:
H-Cys-Val-2-Nal-Met-OH

[Synonym ]:
Cys-Val-2-Nal-Met

Biological Activity

[Description]:

H-Cys-Val-2-Nal-Met-OH is a peptide. H-Cys-Val-2-Nal-Met-OH is a peptidomimetic derivative that can be used to label short peptide sequences[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Boschi A, et al. A novel approach to the high-specific-activity labeling of small peptides with the technetium-99m fragment [99mTc(N)(PXP)]2+ (PXP = diphosphine ligand). Bioconjug Chem. 2001 Nov-Dec;12(6):1035-42.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₆H₃₆N₄O₅S₂

[ Molecular Weight ]:
548.71800

[ Exact Mass ]:
548.21300

[ PSA ]:
214.72000

[ LogP ]:
3.46050

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

Nonfarnesylated tetrapeptide inhibitors of protein farnesyltransferase.

J. Biol. Chem. 266 , 15575-15578, (1991)

The protein farnesyltransferase from rat brain was previously shown to be inhibited competitively by tetrapeptides that conform to the consensus Cys-A1-A2-X, where A1 and A2 are aliphatic amino acids ...

Infectious tolerance via the consumption of essential amino acids and mTOR signaling.

Proc. Natl. Acad. Sci. U. S. A. 106 , 12055-60, (2009)

Infectious tolerance describes the process of CD4(+) regulatory T cells (Tregs) converting naïve T cells to become additional Tregs. We show that antigen-specific Tregs induce, within skin grafts and ...

Hamilton, A.D. and Sebti, S.M

Drug News Perspect. 8 , 138, (1995)