2',3'-cGMP sodium

Names

[ Name ]:
2',3'-cGMP sodium

[Synonym ]:
2':3'-Cycloguanosinphosphat
cyclic 2',3'-(hydrogen phosphate),monosodium salt
guanosine 2':3'-cyclic monophosphate*sodium
guanosine 2',3'-cyclophosphate monosodium salt
Natriumsalz
Guanosine,cyclic 2',3'-(hydrogen phosphate),monosodium salt
Guanosine 2',3'-phosphatesodium salt
guanosine 2',3'-cyclic monophosphate sodium salt

Biological Activity

[Description]:

2',3'-cGMP sodium, a cGMP analogue, is an intermediate of RNA catalytic cleavage by binase[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

2',3'-cGMP sodium (10 nM-100 μM, 120 min) reduces the active transport of [3H]3’,5’-cGMP into inside-out vesicles from human erythrocytes[2]. 2',3'-cGMP sodium (2 μM) increases the ATPase activity[2].

Chemical & Physical Properties

[ Density]:
2.64g/cm3

[ Boiling Point ]:
778.4ºC at 760mmHg

[ Molecular Formula ]:
C₁₀H₁₁N₅NaO₇P

[ Molecular Weight ]:
367.18700

[ Flash Point ]:
424.5ºC

[ Exact Mass ]:
367.02900

[ PSA ]:
187.45000

[ Vapour Pressure ]:
1.67E-25mmHg at 25°C

[ Index of Refraction ]:
2.064

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

Cyclic di-GMP signalling in the virulence and environmental adaptation of Xanthomonas campestris.

Mol. Microbiol. 63(2) , 429-42, (2007)

Cyclic di-GMP is a second messenger with a role in regulation of a range of cellular functions in diverse bacteria including the virulence of pathogens. Cellular levels of cyclic di-GMP are controlled...

Crystal structure of the ffh and EF-G binding sites in the conserved domain IV of Escherichia coli 4.5S RNA.

Structure 8(5) , 527-40, (2000)

Bacterial signal recognition particle (SRP), consisting of 4.5S RNA and Ffh protein, plays an essential role in targeting signal-peptide-containing proteins to the secretory apparatus in the cell memb...

BdlA, a chemotaxis regulator essential for biofilm dispersion in Pseudomonas aeruginosa.

J. Bacteriol. 188(21) , 7335-43, (2006)

Multiple environmental cues have been shown to trigger biofilm detachment, the transition from surface-attached, highly organized communities known as biofilms to the motile lifestyle. The goal of thi...