FXIa-IN-6

Names

[ CAS No. ]:
1551459-37-0

[ Name ]:
FXIa-IN-6

Biological Activity

[Description]:

FXIa-IN-6 is a potent FXIa inhibitor with selectivity against most of the relevant serine proteases (Ki = 0.3 nM).

[Related Catalog]:

Research Areas >> Cardiovascular Disease

Signaling Pathways >> Metabolic Enzyme/Protease >> Factor Xa

[References]

[1]. Yang W, et al. Discovery of a High Affinity, Orally Bioavailable Macrocyclic FXIa Inhibitor with Antithrombotic Activity in Preclinical Species. J Med Chem. 2020 Jul 9;63(13):7226-7242.

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₁H₂₉ClF₂N₄O₄

[ Molecular Weight ]:
595.04

Related Compounds

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