19-Hydroxy-10-deacetylbaccatin III

Names

[ Name ]:
19-Hydroxy-10-deacetylbaccatin III

[Synonym ]:
19-羟基-10-脱乙酰基巴卡亭III

Biological Activity

[Description]:

19-Hydroxy-10-deacetylbaccatin III (compound 13) is a taxane with potential antitumor activity. 19-Hydroxy-10-deacetylbaccatin III has weak cytotoxicity against A498 and NCI-H226 cell lines. The study found that the inhibition rates of 30 μg/mL 19-Hydroxy-10-deacetylbaccatin III on A498, NCI-H226 and PC-3 were 16.6% and 32% respectively[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[References]

[1]. Shen YC, et al. Three new taxane diterpenoids from Taxus sumatrana. J Nat Prod. 2005 Jan;68(1):90-3.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₉H₃₆O₁₁

[ Molecular Weight ]:
560.59