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Cyclo(-Ala-Arg-Gly-Asp-3-aminomethylbenzoyl) trifluoroacetate salt

Names

[ CAS No. ]:
153381-95-4

[ Name ]:
Cyclo(-Ala-Arg-Gly-Asp-3-aminomethylbenzoyl) trifluoroacetate salt

[Synonym ]:
Cyclo(Ala-Arg-Gly-Asp-3-Aminomethylbenzoyl)
XJ735
Cyclo(-Ala-Arg-Gly-Asp-3-aminomethylbenzoyl) trifluoroacetate salt

Biological Activity

[Description]:

Cyclo(Ala-Arg-Gly-Asp-3-aminomethylbenzoyl) is a selective RGD peptide antagonist and has the potential for Pulmonary arterial hypertensionResearch[1].

[Related Catalog]:

Research Areas >> Inflammation/Immunology
Signaling Pathways >> Cytoskeleton >> Integrin

[Target]

IC50: αVβ3 integrin[1]


[References]

[1]. Liukun Meng et al. Osteopontin plays important roles in pulmonary arterial hypertension induced by systemic-to-pulmonary shunt. FASEB J. 2019 Jun;33(6):7236-7251.  

Chemical & Physical Properties

[ Molecular Formula ]:
C23H32N8O7

[ Molecular Weight ]:
532.55

[ Exact Mass ]:
646.23200

[ PSA ]:
282.00000

[ LogP ]:
0.72670

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
22-24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Related Compounds

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