β-glucuronidase substrate
Names
[ CAS No. ]:
15265-26-6
[ Name ]:
β-glucuronidase substrate
[Synonym ]:
(2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[4-[1-(4-hydroxyphenyl)-3-oxo-2-benzofuran-1-yl]phenoxy]oxane-2-carboxylic acid
Chemical & Physical Properties
[ Density]:
1.584g/cm3
[ Boiling Point ]:
804.5ºC at 760mmHg
[ Molecular Formula ]:
C26H22O10
[ Molecular Weight ]:
494.44700
[ Flash Point ]:
276.5ºC
[ Exact Mass ]:
494.12100
[ PSA ]:
162.98000
[ LogP ]:
1.12550
[ Vapour Pressure ]:
2.53E-27mmHg at 25°C
[ Storage condition ]:
20°C
MSDS
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Safety Phrases ]:
22-24/25
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Articles
Biochim. Biophys. Acta 873(2) , 252-9, (1986)
Evidence was found for UDPglucuronyltransferase-catalysed deconjugation of p-nitrophenol-, 4-methylumbelliferone- and phenolphthalein-glucuronides. The evidence is based on the following observations:...
Distribution of chlordecone to liver plasma membranes and recovery from hepatobiliary dysfunction in rats.Toxicology 86(1-2) , 123-34, (1994)
Chlordecone (CD) impairs biliary excretion of organic anions (including phenolphthalein glucuronide (PG), imipramine polar metabolites, and taurocholate) without evidence of hepatocellular necrosis in...
NMR-monitored solid-phase extraction of phenolphthalein glucuronide on phenylboronic acid and C18 bonded phases.J. Pharm. Biomed. Anal. 9(10-12) , 895-9, (1991)
Preliminary studies have been undertaken to evaluate the potential of immobilized phenylboronic acid (PBA) for the solid-phase extraction (SPE) of glucuronide metabolites from urine. These studies hav...