FG-5893

Names

[ CAS No. ]:
150527-23-4

[ Name ]:
FG-5893

[Synonym ]:
fg-5893

Biological Activity

[Description]:

FG-5893 is a 5-HT1A receptor agonist and a 5-HT2 receptor antagonist. FG-5893 has anxiolytic effect[1][2].

[Related Catalog]:

Research Areas >> Neurological Disease

Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor

Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor

[References]

[1]. Gunnar Andersson, et al. Effects of FG 5893, a new compound with 5-HT1A receptor agonistic and 5-HT2 receptor antagonistic properties, on male rat sexual behavior. European Journal of Pharmacology. Volume 255, Issues 1–3, 1 April 1994, Pages 131-137.

[2]. Albinsson A, et al. Preclinical pharmacology of FG5893: a potential anxiolytic drug with high affinity for both 5-HT1A and 5-HT2A receptors. Eur J Pharmacol. 1994 Aug 22;261(3):285-94.

Chemical & Physical Properties

[ Density]:
1.201g/cm3

[ Boiling Point ]:
598.6ºC at 760mmHg

[ Molecular Formula ]:
C₂₇H₂₉F₂N₃O₂

[ Molecular Weight ]:
465.53500

[ Flash Point ]:
315.8ºC

[ Exact Mass ]:
465.22300

[ PSA ]:
45.67000

[ LogP ]:
4.88360

[ Vapour Pressure ]:
2.73E-14mmHg at 25°C

[ Index of Refraction ]:
1.571

Related Compounds

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