3-Hydroxybutyric acid sodium

Names

[ CAS No. ]:
150-83-4

[ Name ]:
3-Hydroxybutyric acid sodium

[Synonym ]:
Sodium 3-hydroxybutanoate
EINECS 205-774-5
Butanoic acid, 3-hydroxy-, sodium salt (1:1)
MFCD00016716
DL-3-HYDROXYBUTYRIC ACID SODIUM SALT
Sodium (3R)-3-hydroxybutanoate
sodium 3-hydroxybutyrate
UNII:19AN4ZH292
Butanoic acid, 3-hydroxy-, sodium salt, (3R)- (1:1)

Biological Activity

[Description]:

3-Hydroxybutyric acid sodium (β-Hydroxybutyric acid sodium) is a metabolite that is elevated in type I diabetes. 3-Hydroxybutyric acid sodium can modulate the properties of membrane lipids[1].

[Related Catalog]:

Research Areas >> Metabolic Disease

[Target]

Human Endogenous Metabolite

[In Vitro]

3-Hydroxybutyric acid sodium (β-Hydroxybutyric acid sodium) is capable of interacting with lipids (modeled using a DPPC monolayer) and altering phase behavior at clinical concentrations. 3-Hydroxybutyric acid sodium also diminishes the interfacial viscosity of DPPC Monolayers[1].

[References]

[1]. Hsu TT, et al. 3-Hydroxybutyric acid interacts with lipid monolayers at concentrations that impair consciousness. Langmuir. 2013 Feb 12;29(6):1948-55.

Chemical & Physical Properties

[ Boiling Point ]:
269.2ºC at 760mmHg

[ Melting Point ]:
165-167ºC

[ Molecular Formula ]:
C₄H₇NaO₃

[ Molecular Weight ]:
126.086

[ Flash Point ]:
121ºC

[ Exact Mass ]:
126.029289

[ PSA ]:
60.36000

[ Vapour Pressure ]:
0.000979mmHg at 25°C

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
205-774-5

[ HS Code ]:
2918199090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2918199090

[ Summary ]:
2918199090 other carboxylic acids with alcohol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Articles

Hormone and Cytokine Responses to Repeated Endotoxin Exposures-No Evidence of Endotoxin Tolerance After 5 Weeks in Humans.

Shock 44 , 32-5, (2015)

Endotoxin administrations are used in experimental models of inflammatory disease. Short-term endotoxin tolerance in response to repeated endotoxin exposure is well known, but the duration of endotoxi...

Related Compounds

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