CP 86325 sodium salt

Names

[ Name ]:
CP 86325 sodium salt

[Synonym ]:
Darglitazone sodium salt
DARGLITAZONE SODIUM
UNII-A1P35HS4XI
CP-86,325-2

Biological Activity

[Description]:

Darglitazone Sodium, a thiazolidinedione, is an orally active, potent, and selective PPAR-γ (peroxisome proliferator-activated receptor) agonist. Darglitazone Sodium is effective in controlling blood glucose and lipid metabolism, and can be used for type II diabetes research[1][2].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> PPAR

Research Areas >> Metabolic Disease

Research Areas >> Neurological Disease

[Target]

PPAR-γ

[References]

[1]. Rashmi Kumari, et al. The PPAR-gamma agonist, darglitazone, restores acute inflammatory responses to cerebral hypoxia-ischemia in the diabetic ob/ob mouse. J Cereb Blood Flow Metab. 2010 Feb;30(2):352-60.

[2]. Hoenig M, Ferguson DC. Effect of darglitazone on glucose clearance and lipid metabolism in obese cats. Am J Vet Res. 2003 Nov;64(11):1409-13.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₃H₁₉N₂NaO₄S

[ Molecular Weight ]:
442.46300

[ Exact Mass ]:
442.09600

[ PSA ]:
120.89000

[ LogP ]:
4.50800

MSDS

Click to get detail MSDS

Safety Information

[ RIDADR ]:
NONH for all modes of transport

Related Compounds

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