1,7-Bis(4-hydroxyphenyl)hepta-1,4,6-trien-3-one

Names

[ Name ]:
1,7-Bis(4-hydroxyphenyl)hepta-1,4,6-trien-3-one

Biological Activity

[Description]:

1,7-Bis(4-hydroxyphenyl)-1,4,6-heptatrien-3-one is a potent nucleocapsid (N) protein inhibitor can be isolated from Curcuma kwangsiensis. 1,7-Bis(4-hydroxyphenyl)-1,4,6-heptatrien-3-one exhibits excellent antiviral activity against HCoV-OC43 and SARS-CoV-2,with EC50 values of 0.16 μM and 0.17 μM, respectively[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> SARS-CoV

[References]

[1]. Yang Liu, et al. 1,7-Bis(4-hydroxyphenyl)-1,4,6-heptatrien-3-one inhibits SARS-CoV-2 by targeting the nucleocapsid protein. Acta Materia Medica. 2023. Vol. 2(3):270-280.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₉H₁₆O₃

[ Molecular Weight ]:
292.33

[ Exact Mass ]:
292.11000

[ PSA ]:
57.53000

[ LogP ]:
3.94970

Related Compounds

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