Nonanal-d18

Nonanal-d18 is the deuterium labeled Nonanal[1]. Nonanal is a saturated fatty aldehyde with antidiarrhoeal activity[2].

Signaling Pathways >> Others >> Others

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Miguel A, et al. Antidiarrhoeal Activity of Nonanal, an Aldehyde Isolated from Artemisia ludoviciana. Pharmaceutical Biology Volume 40, 2002 - Issue 4