7-Deoxy-trans-dihydronarciclasine

Names

[ Name ]:
7-Deoxy-trans-dihydronarciclasine

[Synonym ]:
7-deoxy-trans-dihydro-narciclasine
(+)-trans-dihydrolycoricidine

Biological Activity

[Description]:

7-Deoxy-trans-dihydronarciclasine, an alkaloid, is a tobacco mosaic virus (TMV) inhibitor (IC50: 1.80 μM). 7-Deoxy-trans-dihydronarciclasine is an anti-neuroinflammatory agent. 7-Deoxy-trans-dihydronarciclasine decreases the Aβ and APP levels in the cerebral cortex of Tg2576 mice[1][2][3].

[Related Catalog]:

Research Areas >> Infection

Research Areas >> Inflammation/Immunology

Research Areas >> Neurological Disease

[References]

[1]. Wang YH, et al. Benzylphenethylamine alkaloids from Hosta plantaginea with inhibitory activity against tobacco mosaic virus and acetylcholinesterase. J Nat Prod. 2007 Sep;70(9):1458-61.

[2]. Zhao D, et al. 7-Deoxy-trans-dihydronarciclasine Isolated from Lycoris chejuensis Inhibits Neuroinflammation in Experimental Models. J Agric Food Chem. 2019 Sep 4;67(35):9796-9804.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₄H₁₅NO₆

[ Molecular Weight ]:
293.27200

[ Exact Mass ]:
293.09000

[ PSA ]:
108.25000

Related Compounds

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