TAS-119
Names
[ CAS No. ]:
1453099-83-6
[ Name ]:
TAS-119
Biological Activity
[Description]:
TAS-119 is a potent, selective and orally active Aurora A inhibitor with an IC50 of 1.0 nM. TAS-119 shows high selectivity for Aurora A over other protein kinases, including Aurora B (IC50 of 95 nM). TAS-119 has potent antitumor activites.
Chemical & Physical Properties
[ Molecular Formula ]:
C23H22Cl2FN5O3
[ Molecular Weight ]:
506.36