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TRAP-7 trifluoroacetate salt

Names

[ CAS No. ]:
145229-76-1

[ Name ]:
TRAP-7 trifluoroacetate salt

[Synonym ]:
thrombinreceptorpeptidesfllrnp
SER-PHE-LEU-LEU-ARG-ASN-PRO
SFLLRNP

Biological Activity

[Description]:

TRAP-7 is a thrombin receptor (PAR) activating peptide. TRAP-7 stimulates total inositol phosphate (IP) accumulation and phosphorylation of a specific endogenous substrate for activated PKC. TRAP-7 can be used in cardiovascular disease research[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease
Signaling Pathways >> GPCR/G Protein >> Protease-Activated Receptor (PAR)

[References]

[1]. Webb ML, et al. Effects of thrombin receptor activating peptide on phosphoinositide hydrolysis and protein kinase C activation in cultured rat aortic smooth muscle cells: evidence for "tethered-ligand" activation of smooth muscle cell thrombin receptors. Biochem Pharmacol. 1993 Apr 22;45(8):1577-82.  

Chemical & Physical Properties

[ Density]:
1.41 g/cm3

[ Molecular Formula ]:
C39H63N11O10

[ Molecular Weight ]:
845.98500

[ Exact Mass ]:
845.47600

[ PSA ]:
354.35000

[ LogP ]:
1.76310

[ Index of Refraction ]:
1.64


Related Compounds