RX 871024
Names
[ CAS No. ]:
142872-84-2
[ Name ]:
RX 871024
Biological Activity
[Description]:
A imidazoline compound that stimulate insulin release by inhibition of ATP-dependent K+ channels and inducing of Ca2+ mobilization in mouse pancreatic beta-cells; blocks ATP-dependent K+ channels and membrane depolarization, and activates voltage-dependent Ca2+ channels. Diabetes Discontinued
[References]
References 1. Efanova IB, et al. Diabetes. 1998 Feb;47(2):211-8. 2. Zaitsev SV, et al. Diabetes. 1996 Nov;45(11):1610-8. 3. Mourtada M, et al. Eur J Pharmacol. 1998 Jun 5;350(2-3):251-8. 4. Mourtada M, et al. Br J Pharmacol. 1999 Jul;127(5):1279-87. View Related Products by Target Potassium Channel Diabetes
Chemical & Physical Properties
[ Molecular Formula ]:
C17H15N3·HCl
[ Molecular Weight ]:
297.78
Safety Information
[ RIDADR ]:
NONH for all modes of transport