2-Aminopurine dihydrochloride

Names

[ Name ]:
2-Aminopurine dihydrochloride

[Synonym ]:
9H-Purin-2-amine, hydrochloride (1:2)
9H-Purin-2-amine dihydrochloride

Biological Activity

[Description]:

2-Aminopurine dihydrochloride is a fluorescent analog of guanosine. 2-Aminopurine dihydrochloride can be used as a fluorescence probe for nucleic acid structure and dynamics. Incorporating 2-Aminopurine dihydrochloride into DNA quenches its fluorescence[1][2].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Jean JM, et al. 2-Aminopurine fluorescence quenching and lifetimes: role of base stacking. Proc Natl Acad Sci U S A. 2001 Jan 2;98(1):37-41.

[2]. Rachofsky EL, et al. Probing structure and dynamics of DNA with 2-aminopurine: effects of local environment on fluorescence. Biochemistry. 2001 Jan 30;40(4):946-56.

Chemical & Physical Properties

[ Molecular Formula ]:
C₅H₇Cl₂N₅

[ Molecular Weight ]:
208.049

[ Exact Mass ]:
207.007858

Related Compounds

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