Catestatin TFA

Names

[ Name ]:
Catestatin TFA

[Synonym ]:
NPEC-caged-D-AP5

Biological Activity

[Description]:

Catestatin is a 21-amino acid residue, cationic and hydrophobic peptide. Catestatin is an endogenous peptide that regulates cardiac function and blood pressure[1]. Catestatin is a non-competitive nicotinic antagonist acting through nicotinic acetylcholine receptors (nAChRs) to inhibit catecholamine release[2].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

Signaling Pathways >> Membrane Transporter/Ion Channel >> nAChR

Signaling Pathways >> Neuronal Signaling >> nAChR

[References]

[1]. Nitish R Mahapatra. Catestatin Is a Novel Endogenous Peptide That Regulates Cardiac Function and Blood Pressure. Cardiovasc Res. 2008 Dec 1;80(3):330-8.

[2]. Sebastian Kraszewski, et al. A Molecular Dynamics Study of Catestatin Docked on Nicotinic Acetylcholine Receptors to Identify Amino Acids Potentially Involved in the Binding of Chromogranin A Fragments. Phys Chem Chem Phys. 2015 Jul 14;17(26):17454-60.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₀₇H₁₇₃N₃₇O₂₆S

[ Molecular Weight ]:
2326.68000

[ Exact Mass ]:
2325.22000

[ PSA ]:
988.77000

[ LogP ]:
2.06660

Related Compounds

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