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Ammonium Glycyrrhizinate

Names

[ CAS No. ]:
1407-03-0

[ Name ]:
Ammonium Glycyrrhizinate

[Synonym ]:
Ammonium Glycyrrhizinate

Biological Activity

[Description]:

Ammonium glycyrrhizinate is a triterpenoid saponin, acting as a direct HMGB1 antagonist, with anti-inflammatory， anti-tumor, anti-diabetic activities[1][2][3].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others
Research Areas >> Inflammation/Immunology

[Target]

HMGB1[1]


[References]

[1]. Li C, et al. Glycyrrhizin, a Direct HMGB1 Antagonist, Ameliorates Inflammatory Infiltration in a Model of Autoimmune Thyroiditis via Inhibition of TLR2-HMGB1 Signaling. Thyroid. 2017 May;27(5):722-731.

[2]. Su X, et al. Glycyrrhizic acid: A promising carrier material for anticancer therapy. Biomed Pharmacother. 2017 Nov;95:670-678.

Chemical & Physical Properties

[ Boiling Point ]:
971.4ºC at 760 mmHg

[ Molecular Formula ]:
C42H65NO16

[ Molecular Weight ]:
839.96300

[ Flash Point ]:
288.1ºC

[ Exact Mass ]:
839.43000

[ PSA ]:
270.28000

[ LogP ]:
2.56950

[ Vapour Pressure ]:
0mmHg at 25°C

[ Storage condition ]:
2-8°C

Safety Information

[ WGK Germany ]:
2

[ RTECS ]:
LZ6500000

Related Compounds