EZH2-IN-5

Names

[ Name ]:
EZH2-IN-5

Biological Activity

[Description]:

EZH2-IN-5 is a potent EZH2 inhibitor with IC50 values of 1.52 nM and 4.07 nM for wild-type and mutant Tyr641 EZH2, respectively[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Epigenetics >> Histone Methyltransferase

[Target]

EZH2 WT:1.52 nM (IC50)

EZH2 Y641F mutant type:4.07 nM (IC50)

[In Vitro]

EZH2-IN-5 (compound 276) inhibits cell growth of WSUDLCL2 cell lines with an IC50 of 187.28 nM[1].

[References]

[1]. Richard Chesworth, et al. Substituted benzene compounds. WO2012142513A1

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₆H₃₇BrN₄O₂

[ Molecular Weight ]:
517.50

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.