Imidacloprid
Names
[ CAS No. ]:
138261-41-3
[ Name ]:
Imidacloprid
[Synonym ]:
1-((6-chloropyridin-3-yl)methyl)-3-nitroimidazolidin-2-imine
MFCD01721131
EINECS 200-835-2
Imidacloprid
1-((6-Chloro-3-pyridinyl)methyl)-N-nitro-imidazolidinimine
Biological Activity
[Description]:
[Related Catalog]:
[In Vitro]
[In Vivo]
[Animal admin]
[References]
[Related Small Molecules]
Chemical & Physical Properties
[ Density]:
1.6±0.1 g/cm3
[ Boiling Point ]:
442.3±55.0 °C at 760 mmHg
[ Melting Point ]:
144ºC
[ Molecular Formula ]:
C9H10ClN5O2
[ Molecular Weight ]:
255.661
[ Flash Point ]:
221.3±31.5 °C
[ Exact Mass ]:
255.052307
[ PSA ]:
89.04000
[ LogP ]:
-0.43
[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C
[ Index of Refraction ]:
1.706
[ Storage condition ]:
0-6°C
[ Water Solubility ]:
0.061 g/100mL at 20 ºC
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- NJ0560000
- CHEMICAL NAME :
- 2-Imidazolidinimine, 1-((6-chloro-3-pyridinyl)methyl)-N-nitro-
- CAS REGISTRY NUMBER :
- 138261-41-3
- LAST UPDATED :
- 199806
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C9-H10-Cl-N5-O2
- MOLECULAR WEIGHT :
- 255.69
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 410 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AGJAEP Agrochemcicals Japan. (Japan Plant Protection Association, 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) No.62- 1993- Volume(issue)/page/year: (63),15,1993
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >5323 mg/m3
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AGJAEP Agrochemcicals Japan. (Japan Plant Protection Association, 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) No.62- 1993- Volume(issue)/page/year: (63),15,1993
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >5 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AGJAEP Agrochemcicals Japan. (Japan Plant Protection Association, 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) No.62- 1993- Volume(issue)/page/year: (63),15,1993
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 98 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NNGADV Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. (Nippon Noyaku Gakkai, 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) V.1- 1976- Volume(issue)/page/year: 19,S209,1994 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 4550 mg/kg/13W-C
- TOXIC EFFECTS :
- Behavioral - food intake (animal) Nutritional and Gross Metabolic - weight loss or decreased weight gain
- REFERENCE :
- TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 36(1,pt2),64,1997
Safety Information
[ Symbol ]:
GHS02, GHS07
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H225-H302-H312-H319-H332
[ Precautionary Statements ]:
P210-P280-P305 + P351 + P338
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
N: Dangerous for the environment;Xn: Harmful;F: Flammable;
[ Risk Phrases ]:
R11
[ Safety Phrases ]:
26-36-22
[ RIDADR ]:
UN 2588
[ RTECS ]:
NJ0560000
[ Packaging Group ]:
III
[ Hazard Class ]:
6.1(b)
[ HS Code ]:
2933399026
Customs
[ HS Code ]: 2933399026
Articles
Environ. Sci. Pollut. Res. Int. 21(14) , 8387-97, (2014)
The oxidative degradation of imidacloprid (ICP) has been carried out by electrochemical advanced oxidation processes (EAOPs), anodic oxidation, and electro-Fenton, in which hydroxyl radicals are gener...
Evaluation of imidacloprid-induced neurotoxicity in male rats: a protective effect of curcumin.Neurochem. Int. 78 , 122-9, (2014)
The present study was carried out to evaluate the neurotoxic effect and biochemical alteration as a result of imidacloprid (IMI) exposure and potential protective role of curcumin (Cur) against it in ...
Capillary electrophoresis-mass spectrometry as a new approach to analyze neonicotinoid insecticides.J. Chromatogr. A. 1359 , 317-24, (2014)
This paper represents the first report of a capillary electrophoresis (CE) method compatible with mass spectrometry (MS) detection for simultaneously analyzing seven neonicotinoid insecticides (acetam...