win-62577

Names

[ CAS No. ]:
138091-43-7

[ Name ]:
win-62577

[Synonym ]:
HMS2234A21
17-|A-Hydroxy-17-|A-ethynyl-|A-4-androstano[3,2-b]pyrimido[1,2-a]benzimidazole

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₉H₃₁N₃O

[ Molecular Weight ]:
437.57600

[ Exact Mass ]:
437.24700

[ PSA ]:
50.42000

[ LogP ]:
5.42890

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

Synthesis and substance P receptor binding activity of androstano[3,2-b]pyrimido[1,2-a]benzimidazoles.

J. Med. Chem. 35 , 374, (1992)

Several heterosteroids containing a dihydroethisterone skeleton were prepared and shown to displace substance P in a receptor binding assay. Further biochemical (kinetic and Scatchard analyses) and ph...

Antagonists that demonstrate species differences in neurokinin-1 receptors.

Mol. Pharmacol. 41 , 772, (1992)

125I-Bolton-Hunter-substance P (125I-BH-SP) binding properties of three novel classes of neurokinin-1 (NK-1) receptor antagonists were investigated in tissues derived from humans, guinea pigs, and rat...

Related Compounds

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