Cyclo(-Gly-Arg-Gly-Asp-Ser-Pro) trifluoroacetate salt

Names

[ Name ]:
Cyclo(-Gly-Arg-Gly-Asp-Ser-Pro) trifluoroacetate salt

Biological Activity

[Description]:

Cyclo(Gly-Arg-Gly-Asp-Ser-Pro) (c(GRGDSP)) is an RGD-containing inhibitory peptide. Cyclo(Gly-Arg-Gly-Asp-Ser-Pro) is a synthetic α5β1 integrin ligand that competitively inhibits the binding of invasin (Inv) to α5β1 integrin expressed on Caco-2 cells[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cytoskeleton >> Integrin

[References]

[1]. Kumagai H, et al. Effect of cyclic RGD peptide on cell adhesion and tumor metastasis. Biochem Biophys Res Commun. 1991 May 31;177(1):74-82.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₂H₃₅N₉O₉

[ Molecular Weight ]:
569.58