RR6

Names

[ Name ]:
RR6

[Synonym ]:
MFCD27664963
(2R)-2,4-Dihydroxy-3,3-dimethyl-N-(3-oxo-4-phenylbutyl)butanamide
Butanamide, 2,4-dihydroxy-3,3-dimethyl-N-(3-oxo-4-phenylbutyl)-, (2R)-

Biological Activity

[Description]:

RR6 is a selective, reversible, and competitive vanin inhibitor.target: vaninIn vivo: Oral administration of RR6 in rats completely inhibited plasma vanin activity and caused alterations of plasma lipid concentrations upon fasting, thereby illustrating its potential use in chemical biology research. RR6 at 3 mg/mL inrats caused a nearly complete inhibition of plasma vanin.

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Cancer

[References]

[1]. Jansen PA et al. Discovery of small molecule vanin inhibitors: new tools to study metabolism and disease. ACS Chem Biol. 2013 Mar 15;8(3):530-4.

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
559.5±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₆H₂₃NO₄

[ Molecular Weight ]:
293.358

[ Flash Point ]:
292.2±30.1 °C

[ Exact Mass ]:
293.162720

[ LogP ]:
0.71

[ Vapour Pressure ]:
0.0±1.6 mmHg at 25°C

[ Index of Refraction ]:
1.542

[ Storage condition ]:
2-8℃

Related Compounds

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