(+)-Clopidogrel bisulfate

Names

[ Name ]:
(+)-Clopidogrel bisulfate

[Synonym ]:
MFCD00876395
Plavix
Clopidogrel Hydrogen sulfate
Methyl (2S)-(2-chlorophenyl)(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetate sulfate
methyl (2S)-(2-chlorophenyl)(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)ethanoate sulfate
methyl (2S)-(2-chlorophenyl)(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)ethanoate sulfate (1:1)
Clopidogrel bisulfate
(2S)-(2-chlorophényl)(6,7-dihydrothiéno[3,2-c]pyridin-5(4H)-yl)éthanoate de méthyle sulfate
Clopidogrel Hydrogensulfate
Thieno[3,2-c]pyridine-5(4H)-acetic acid, α-(2-chlorophenyl)-6,7-dihydro-, methyl ester, (αS)-, sulfate (1:1)
(+)-Clopidogrel hydrogen sulfate
Clopidogrel bisulphate
(S)-(+)-Methyl (2-chlorophenyl)(6,7-dihydro-4H-thieno[3,2-c]pyrid-5-yl)acetate bisulfate
Methyl (2S)-(2-chlorophenyl)(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetate sulfate (1:1)
a-(S)-(2-Chlorophenyl)-6,7-dihydrothieno[3,2-c]pyridine-5(4H)-acetic Acid Methyl Ester Sulfate (1:1)
Methyl aS-(2-Chlorophenyl)-6,7-dihydrothieno[3,2-c]pyridine-5(4H)-acetate Sulfate (1:1)
Methyl-(2S)-(2-chlorphenyl)(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)ethanoatsulfat
S-(+)-Clopidogrel Hydrogen Sulfate

Biological Activity

[Description]:

Clopidogrel sulfate is an antiplatelet agent. Specifically, Clopidogrel sulfate inhibits the binding of ADP to its receptors on the membranes of platelet cells, and blocks ADP-mediated activation of the glycoprotein GPIIb/IIIa complex. Clopidogrel sulfate can be used for research of heart disease and stroke[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

Signaling Pathways >> Others >> Others

[References]

[1]. Pindelska E, et al. Solid-state NMR as an effective method of polymorphic analysis: solid dosage forms of clopidogrel hydrogensulfate. J Pharm Sci. 2015 Jan;104(1):106-13.

Chemical & Physical Properties

[ Boiling Point ]:
423.7ºC at 760 mmHg

[ Melting Point ]:
184ºC

[ Molecular Formula ]:
C₁₆H₁₈ClNO₆S₂

[ Molecular Weight ]:
419.900

[ Flash Point ]:
210ºC

[ Exact Mass ]:
419.026398

[ PSA ]:
140.76000

[ LogP ]:
4.03980

[ Vapour Pressure ]:
8.71E-09mmHg at 25°C

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
T+

[ Safety Phrases ]:
22-24/25

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2934999090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%