2-(diethylamino)-4-methylpentyl 4-aminobenzoate, monomethanesulphonate
Names
[ CAS No. ]:
135-44-4
[ Name ]:
2-(diethylamino)-4-methylpentyl 4-aminobenzoate, monomethanesulphonate
[Synonym ]:
2-Diethylamino-4-methyl-1-pentanol 4-aminobenoate monomethanesulfonate
4-Amino-benzoesaeure-(2-diaethylamino-4-methyl-pentylester),Methansulfonat
4-amino-benzoic acid-(2-diethylamino-4-methyl-pentylester),methanesulfonate
Leucinocaine methanesulfonate
monomethanesulfonate (salt)
Leucinocainmesilat
Leucinocaine
Leucinocaine mesylate
Panthesine
2-(diethylamino)-4-methyl-1-pentanol
monomethanesulfonate
EINECS 205-191-6
Panthesin
4-aminobenzoate (ester)
Chemical & Physical Properties
[ Boiling Point ]:
417.1ºC at 760mmHg
[ Molecular Formula ]:
C18H32N2O5S
[ Molecular Weight ]:
388.52200
[ Flash Point ]:
206ºC
[ Exact Mass ]:
388.20300
[ PSA ]:
118.31000
[ LogP ]:
4.34810
[ Vapour Pressure ]:
3.65E-07mmHg at 25°C
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- SA6475000
- CHEMICAL NAME :
- 1-Pentanol, 2-(diethylamino)-4-methyl-, p-aminobenzoate (ester), monomethanesulfonate
- CAS REGISTRY NUMBER :
- 135-44-4
- LAST UPDATED :
- 199012
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C17-H28-N2-O2.C-H4-O3-S
- MOLECULAR WEIGHT :
- 388.58
- WISWESSER LINE NOTATION :
- ZR DVO1YN2&2&1Y1&1 &OSW1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 300 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PHREA7 Physiological Reviews. (American Physiological Soc., 9650 Rockville Pike, Bethesda, MD 20814) V.1- 1921- Volume(issue)/page/year: 12,190,1932
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 49 mg/kg
- TOXIC EFFECTS :
- Behavioral - general anesthetic
- REFERENCE :
- WDMU** "Vergleichend-pharmakologische Untersuchungen ueber die haemolytische Wirkung und die Toxizitat der Lokalanaesthetika, Dissertation," Walther, M., Pharmakologischen Instit Martin Luther-Universitat Halle-Wittenburg, Ger. Dem. Rep., 1936 Volume(issue)/page/year: -,-,1936
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 240 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PHREA7 Physiological Reviews. (American Physiological Soc., 9650 Rockville Pike, Bethesda, MD 20814) V.1- 1921- Volume(issue)/page/year: 12,190,1932
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 20 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 57,221,1936
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraspinal
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 10200 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 54,137,1935
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 112 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PHREA7 Physiological Reviews. (American Physiological Soc., 9650 Rockville Pike, Bethesda, MD 20814) V.1- 1921- Volume(issue)/page/year: 12,190,1932
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 20 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PHREA7 Physiological Reviews. (American Physiological Soc., 9650 Rockville Pike, Bethesda, MD 20814) V.1- 1921- Volume(issue)/page/year: 12,190,1932
Safety Information
[ HS Code ]:
2922499990
Customs
[ HS Code ]: 2922499990
[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%