WWL 123

Names

[ Name ]:
WWL 123

[Synonym ]:
WWL123
N-[[1,1'-Biphenyl]-3-ylmethyl)-N-methylcarbamic acid 4'-(aminocarbonyl)[1,1'-biphenyl]-4-yl ester
Carbamic acid, N-([1,1'-biphenyl]-3-ylmethyl)-N-methyl-, 4'-(aminocarbonyl)[1,1'-biphenyl]-4-yl ester
4'-Carbamoyl-4-biphenylyl (3-biphenylylmethyl)methylcarbamate

Biological Activity

[Description]:

WWL123, a carbamate-based compound, is a potent and selective ABHD6 inhibitor. WWL123 can be used for research of inflammation, metabolic disorders (obesity and type II diabetes mellitus) and epilepsy[1].

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> MAGL

Research Areas >> Inflammation/Immunology

[References]

[1]. Patel JZ, et al. Revisiting 1,3,4-Oxadiazol-2-ones: Utilization in the Development of ABHD6 Inhibitors. Bioorg Med Chem. 2015 Oct 1;23(19):6335-45.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
646.2±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₈H₂₄N₂O₃

[ Molecular Weight ]:
436.50

[ Flash Point ]:
344.6±31.5 °C

[ Exact Mass ]:
436.178680

[ LogP ]:
5.20

[ Vapour Pressure ]:
0.0±1.9 mmHg at 25°C

[ Index of Refraction ]:
1.631

Related Compounds

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