4,15-Isoatriplicolide methylacrylate

Names

[ CAS No. ]:
133559-38-3

[ Name ]:
4,15-Isoatriplicolide methylacrylate

[Synonym ]:
2-Propenoic acid, 2-methyl-, (3aS,4R,6R,11aR)-2,3,3a,4,5,6,7,10,11,11a-decahydro-6-methyl-3,10-bis(methylene)-2,7-dioxo-6,9-epoxycyclodeca[b]furan-4-yl ester
(4R,8S,9R,11R)-11-Methyl-2,7-bis(methylene)-6,12-dioxo-5,14-dioxatricyclo[9.2.1.04,8]tetradec-1(13)-en-9-yl methacrylate

Biological Activity

[Description]:

4,15-Isoatriplicolide methylacrylate is a germacrane-type sesquiterpene lactone. 4,15-Isoatriplicolide methylacrylate also is a cytotoxic agent. 4,15-Isoatriplicolide methylacrylate has cytotoxic activity for MCF-7 human breast cancer cell line[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[References]

[1]. Li Pan, et al. Bioactive constituents of Helianthus tuberosus (Jerusalem artichoke). Phytochemistry Letters 2 (2009) 15-18.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
552.5±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C19H20O6

[ Molecular Weight ]:
344.358

[ Flash Point ]:
244.1±30.2 °C

[ Exact Mass ]:
344.125977

[ LogP ]:
1.93

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.551

Related Compounds

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