Azido-PEG7-amine

Names

[ CAS No. ]:
1333154-77-0

[ Name ]:
Azido-PEG7-amine

[Synonym ]:
α-(2-aminoethyl)-ω-(2-azidoethoxy)hexa(oxyethylene)

Biological Activity

[Description]:

Azido-PEG7-amine is a non-cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[Target]

Non-cleavable

[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

[References]

[1]. Kevin W. Gillman, et al. Macrocyclic peptides useful as immunomodulators. WO2016077518A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₆H₃₄N₄O₇

[ Molecular Weight ]:
394.46400

[ Exact Mass ]:
394.24300

[ PSA ]:
140.38000

[ LogP ]:
0.52466

Related Compounds

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